Patient-reported outcomes following abiraterone acetate plus prednisone added to androgen deprivation therapy in patients with newly diagnosed metastatic castration-naive prostate cancer (LATITUDE): an international, randomised phase 3 trial.
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| Abstract |    :  
                  In the LATITUDE trial, addition of abiraterone acetate plus prednisone to androgen deprivation therapy (ADT) improved overall survival compared with placebos plus ADT in patients with newly diagnosed, high-risk, metastatic castration-naive prostate cancer. Understanding the effects of treatments on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) is important for treatment decisions; therefore we aimed to analyse the effects of ADT plus abiraterone acetate and prednisone versus ADT plus placebos on PROs and HRQOL in patients in the LATITUDE study.  | 
        
| Year of Publication |    :  
                  2018 
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| Journal |    :  
                  The Lancet. Oncology 
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| Date Published |    :  
                  2018 
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| ISSN Number |    :  
                  1470-2045 
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| DOI |    :  
                  10.1016/S1470-2045(17)30911-7 
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| Short Title |    :  
                  Lancet Oncol 
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