BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
| Author | |
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| Abstract | :
Blood vessel epicardial substance (BVES) is a tight junction-associated protein that regulates epithelial-mesenchymal states and is underexpressed in epithelial malignancy. However, the functional impact of BVES loss on tumourigenesis is unknown. Here we define the in vivo role of BVES in colitis-associated cancer (CAC), its cellular function and its relevance to patients with IBD. |
| Year of Publication | :
2017
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| Journal | :
Gut
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| Volume | :
66
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| Issue | :
5
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| Number of Pages | :
852-862
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| ISSN Number | :
0017-5749
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| URL | :
https://gut.bmj.com/lookup/pmidlookup?view=long&pmid=28389570
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| DOI | :
10.1136/gutjnl-2015-310255
|
| Short Title | :
Gut
|
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